The area was originally inhabited by Native Americans, but was settled by non-indigenous people in 1825. A post office named "Moulin Rouge" was established there in December 1857. Robert Inkster, a Scotsman born March 27, 1828, in Lerwick, Shetland, operated a steam sawmill on present-day Inkster Road near Michigan Avenue in the early 1860s.

The post office was renamed Inkster in July 1863. The village had a station on the Michigan Central Railroad by 1878. It incorporated as a village in 1926 from parts of Nankin Township and Dearborn Township. After much legal wrangling by the city of Dearborn, Dearborn Township, and the village of Inkster to sort out final borders for these communities, Inkster was incorporated as a city in 1964.

Around the 1920s and 1930s black people working in Henry Ford's factories settled in Inkster because they did not want to commute from Detroit and they were not allowed to live in Dearborn.

SOURCE: Wikipedia